Talk to the Veterans Crisis Line now
U.S. flag
An official website of the United States government
ORD only    All VA Research websites

Office of Research & Development

print icon sign up for VA Research updates

Funded Project Details - FY2021

Project Number:

Title: Orexin and serotonin interactions to promote physical activity and prevent obesity
Principal Investigator:

Catherine M. Kotz

Location: Minneapolis, MN
Congressional District Code: 5
Research Service: Biomedical Laboratory R&D
Project Period: October 2017 - September 2022
FY 2021 Funding Amount: $41,523
Total Award Amount
(all years):
Abstract: View full abstract and other project information on NIH RePORTER


The overall goal of this proposal is to identify strategies that target the orexin brain network that regulates spontaneous physical activity, and the associated caloric expenditure. This energy expenditure is referred to as non-exercise activity thermogenesis (NEAT), and we propose that this can be exploited to develop new therapies for weight gain prevention and weight loss in those unable to exercise. The specific objectives are to determine which sub-population of orexin neurons are associat...

Questions about the R&D website? Email the Web Team.

Any health information on this website is strictly for informational purposes and is not intended as medical advice. It should not be used to diagnose or treat any condition.