Office of Research & Development |
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Project Number: | I01BX001660-05A2 |
Title: | Innate inflammation in osteoarthritis |
Principal Investigator: | Robert A. Terkeltaub |
Location: | San Diego, CA |
Congressional District Code: | 52 |
Research Service: | Biomedical Laboratory R&D |
Project Period: | April 2017 - September 2021 |
FY 2021 Funding Amount: | $112,500 |
Total Award Amount (all years): |
$791,074 |
Abstract: |
View full abstract and other project information on NIH RePORTER Go To NIH RePORTER Excerpt: Osteoarthritis (OA) is a major cause of disability in the USA, particularly so in veterans, who are disproportionately affected by aging and joint trauma. OA culminates in failure of the joint, which includes compromised cartilage chondrocyte differentiation and function, by mechanisms that are not completely understood. Because there is no disease-modifying medical therapy for OA, there is major unmet need to advance translation. Our long-term objective is to validate novel targets to limit OA... |