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Funded Project Details - FY2021




Project Number:

I01BX003751-01A1
Title: Impact of TPO Treatment on Bone Healing and Angiogenesis in Type 2 Diabetes
Principal Investigator:

Melissa Kacena

Location: Indianapolis, IN
Congressional District Code: 7
Research Service: Biomedical Laboratory R&D
Project Period: July 2017 - June 2022
FY 2021 Funding Amount: $226,520
Total Award Amount
(all years):
$1,207,767
Abstract: View full abstract and other project information on NIH RePORTER
Go To NIH RePORTER


Excerpt:

Currently, 1 in 4 veterans receiving VA care is diabetic, and over 70% are overweight or obese and at risk of developing diabetes. Diabetes is a risk factor for impaired fracture healing and numerous studies have demonstrated increased frequency of non-union, partial union, or delayed union in diabetic patients as compared to non-diabetic patients. Diabetic patients have impaired microcirculation which is partially responsible for these fracture complications. In the case of non-union, additiona...



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