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Project Number: | I01BX002025-05 |
| Title: | Role of Collagen Binding Receptors in Glomerulosclerosis |
| Principal Investigator: | Ambra Pozzi |
| Location: | Nashville, TN |
| Congressional District Code: | 5 |
| Research Service: | Biomedical Laboratory R&D |
| Project Period: | October 2017 - September 2021 |
| FY 2021 Funding Amount: | $165,000 |
| Total Award Amount (all years): |
$746,331 |
| Abstract: |
View full abstract and other project information on NIH RePORTER Go To NIH RePORTER Excerpt: Abstract Glomerulosclerosis is one of the hallmarks of end stage kidney disease and it is characterized by the replacement of the glomerular tissue with extracellular matrix components (mainly collagens) leading to the loss of functioning glomeruli. The goal of this grant is to investigate the molecular mechanisms that underlie the modulation of collagen turnover in injured glomeruli to devise more effective therapies to prevent glomerulosclerosis. Although many pathways have been implicated in... |