Funded Project Details - FY2021
|Title:|| Role of Cerebrovascular cells in tau processing following traumatic brain injury|
||Bay Pines, FL
|Congressional District Code:
||Biomedical Laboratory R&D
|| July 2018 -
|FY 2021 Funding Amount:
|Total Award Amount
View full abstract and other project information on NIH RePORTER
Go To NIH RePORTER
One of the prominent pathological features of traumatic brain injury (TBI) is the accumulation of hyperphosphorylated and aggregated tau species in the brain. Tau is a cytoplasmic protein which is believed to be restricted to the intracellular compartment of neurons. However, several recent studies have investigated the existence and role for tau in the extracellular compartments of the brain, and have indicated that increased levels of monomeric tau in the extracellular environment play a major...
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