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Funded Project Details - FY2021

Project Number:

Title: Profiling Alzheimer's Biomarkers
Principal Investigator:

Weiming Xia

Location: Bedford, MA
Congressional District Code: 6
Research Service: Biomedical Laboratory R&D
Project Period: October 2017 - September 2021
FY 2021 Funding Amount: $165,000
Total Award Amount
(all years):
Abstract: View full abstract and other project information on NIH RePORTER


Abstract With our unique multi-component clinical sample and advances in Mass Spectrometry (MS), we hope to identify a combination of multiple biomarkers that provide discriminatory and accurate biomarkers of Alzheimer’s disease (AD) to advance earlier detection and treatment. Currently, the ratio of tau/Aβ in cerebrospinal fluid (CSF) is the best available biomarker for separating AD from normal subjects and predicting disease progression, but its sensitivity and specificity are modest. Our co...

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