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Project Number: | IK2BX003922-01 |
| Title: | T-cell regulation of cardiac remodeling |
| Principal Investigator: | Kristine DeLeon-Pennell |
| Location: | Charleston, SC |
| Congressional District Code: | 3 |
| Research Service: | Biomedical Laboratory R&D |
| Project Period: | June 2017 - May 2022 |
| FY 2021 Funding Amount: | $207,916 |
| Total Award Amount (all years): |
$1,020,215 |
| Abstract: |
View full abstract and other project information on NIH RePORTER Go To NIH RePORTER Excerpt: Veterans have 2-times higher risk of developing cardiovascular disease compared to non-veterans. For veterans who have a heart attacked (myocardial infarction; MI), 1 in 3 will not survive 1 year after the event compared to 1 in 10 in the general population. The goal of my project is to understand how the wound healing response after MI can promote the development of heart failure. My focus is the innate immune response, specifically the role of CD8+ T-cells. My central hypothesis is that CD8+ e... |