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Funded Project Details - FY2021

Project Number:

Title: A Novel Small Molecule Inhibitor of Sclerostin to Improve Surgical Spine Fusions In Vivo
Principal Investigator:

Steven M Presciutti

Location: Decatur, GA
Congressional District Code: 4
Research Service: Biomedical Laboratory R&D
Project Period: July 2017 - June 2022
FY 2021 Funding Amount: $426,496
Total Award Amount
(all years):
Abstract: View full abstract and other project information on NIH RePORTER


Spinal arthrodesis procedures are commonly performed in our veterans for a wide range of pathology. Despite state-of-the-art surgical procedures, fusion failure rates still range from 10-40%. This is important, as failure to fuse is often associated with continued pain, worse outcomes, increased medication requirements, and possibly the cost of additional surgeries. Given the individual shortcomings of the currently available bone graft options, there is a clear clinical need for additional stra...

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