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Funded Project Details - FY2021




Project Number:

IK2BX003804-01
Title: Alzheimer's disease-associated tau toxicity induces cellular senescence in the brain.
Principal Investigator:

Miranda Orr

Location: Salisbury, NC
Congressional District Code: 21
Research Service: Biomedical Laboratory R&D
Project Period: July 2017 - June 2022
FY 2021 Funding Amount: $208,004
Total Award Amount
(all years):
$1,006,499
Abstract: View full abstract and other project information on NIH RePORTER
Go To NIH RePORTER


Excerpt:

Tau protein aggregation is the most common pathology among neurodegenerative diseases, which collectively are termed “tauopathies.” These diseases encompass over 15 distinct disorders that greatly affect Veterans, including Alzheimer's disease (AD) and traumatic brain injury. As the most common cause of dementia in the United States, AD affects more than 5 million Americans, including 600,000 military personnel and costs $200 billion per year. Effective treatment strategies remain elusive. We ar...



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