Funded Project Details - FY2021
|Title:|| Gut reservoir of E. coli ST131|
James R. Johnson
|Congressional District Code:
||Clinical Science R&D
|| April 2017 -
|FY 2021 Funding Amount:
|Total Award Amount
View full abstract and other project information on NIH RePORTER
Go To NIH RePORTER
A new Escherichia coli strain called ST131-H30 – unknown prior to 2000 – is now the single most common cause of E. coli infections such as urinary tract infections, particularly those associated with resistance to first- line antibiotics. Veterans are especially vulnerable to ST131-H30, which causes 25-30% of all their E. coli infections, and 70-75% of those involving fluoroquinolone (e.g., ciprofloxacin) resistance. Gut colonization is an important upstream step in ST131-H30 infections, and the...
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