Funded Project Details - FY2021
|Title:|| Cardiovascular Mechanisms of Exercise Intolerance in Diabetes and the Role of Sex|
Jane E.B. Reusch
|Congressional District Code:
||Clinical Science R&D
|| July 2017 -
|FY 2021 Funding Amount:
|Total Award Amount
View full abstract and other project information on NIH RePORTER
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Statement of Problem: Type 2 Diabetes (T2D) affects 24% of Veterans and it is associated with impaired cardiovascular exercise capacity (CVEC) which is important because of a strong relationship between CVEC and excess mortality. The goal of this proposal is to understand the contribution of preclinical cardiac, vascular dysfunction and skeletal muscle perfusion abnormalities to impaired CVEC in men and women with T2D and, further, to test the adaptive response to intervention using exercise tra...
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