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Project Number: | I01CX001283-01A2 |
| Title: | Parenchymal and airway CD4 T cells in protection against pulmonary tuberculosis |
| Principal Investigator: | Richard F. Silver |
| Location: | Cleveland, OH |
| Congressional District Code: | 11 |
| Research Service: | Clinical Science R&D |
| Project Period: | January 2018 - December 2022 |
| FY 2021 Funding Amount: | $75,000 |
| Total Award Amount (all years): |
$697,846 |
| Abstract: |
View full abstract and other project information on NIH RePORTER Go To NIH RePORTER Excerpt: Tuberculosis (TB) remains a significant international public health threat, particularly for US military personnel who are often deployed to areas of high TB prevalence. Mycobacterium tuberculosis (Mtb) is a respiratory pathogen spread via inhalation of infectious airborne particles. Most infected individuals develop protective immunity that serves to contain the organism, but approximately 10% will eventually develop active TB. The localization of mycobacteria-specific CD4+ T cells to the lung... |