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Funded Project Details - FY2021

Project Number:

Title: Parenchymal and airway CD4 T cells in protection against pulmonary tuberculosis
Principal Investigator:

Richard F. Silver

Location: Cleveland, OH
Congressional District Code: 11
Research Service: Clinical Science R&D
Project Period: January 2018 - December 2022
FY 2021 Funding Amount: $75,000
Total Award Amount
(all years):
Abstract: View full abstract and other project information on NIH RePORTER


Tuberculosis (TB) remains a significant international public health threat, particularly for US military personnel who are often deployed to areas of high TB prevalence. Mycobacterium tuberculosis (Mtb) is a respiratory pathogen spread via inhalation of infectious airborne particles. Most infected individuals develop protective immunity that serves to contain the organism, but approximately 10% will eventually develop active TB. The localization of mycobacteria-specific CD4+ T cells to the lung...

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