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Funded Project Details - FY2021

Project Number:

Title: Dysregulated Immune State in PTSD Contributes to Microglial Inflammation
Principal Investigator:

Zhewu J. Wang

Location: Charleston, SC
Congressional District Code: 1
Research Service: Clinical Science R&D
Project Period: July 2017 - May 2022
FY 2021 Funding Amount: $223,750
Total Award Amount
(all years):
Abstract: View full abstract and other project information on NIH RePORTER


Over 2.5 million U.S. service members have been deployed to Afghanistan or Iraq war zones since 2002 and, according to reports from the Department of Veterans Affairs, one in every six returns from this OEF/OIF arena with PTSD. Since only half of the Veterans with PTSD response to treatment, alternate treatment approaches need to be explored. PTSD consists not only clusters of clinical symptoms, but also immune imbalances toward an inflammatory state. Studies of humans and with animal models hav...

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