Funded Project Details - FY2021
|Title:|| Cognitive and Brain Changes in Preclinical Alzheimer's Disease|
Christina E. Wierenga
||San Diego, CA
|Congressional District Code:
||Clinical Science R&D
|| April 2017 -
|FY 2021 Funding Amount:
|Total Award Amount
View full abstract and other project information on NIH RePORTER
Go To NIH RePORTER
The pathogenesis of Alzheimer’s disease (AD) remains unclear, though there is growing support for a synergistic relationship between vascular dysfunction and accumulation of amyloid-β and neurofibrillary tangles. Cerebrovascular disease (CVD) risk factors are prevalent in the VA population, have been linked to cognitive decline and higher risk for dementia, and may represent potential targets for remediating age-related cognitive decline. [CVD risk factors are associated with peripheral vascular...
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