Funded Project Details - FY2021
|Title:|| SCI Consortium Study: Enhancing Corticospinal Tract Axonal Regeneration After Spinal Cord Injury|
Pengzhe (Paul) Lu
||San Diego, CA
|Congressional District Code:
|| July 2017 -
|FY 2021 Funding Amount:
|Total Award Amount
View full abstract and other project information on NIH RePORTER
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Project Summary Corticospinal tract (CST) is an important supraspinal descending motor system that controls voluntary movement in humans. Good progress has been made in recent years to elicit CST axonal regeneration and re-connectivity after spinal cord injury (SCI). For example, conditional deletion of phosphatase and tensin homolog (PTEN) or pharmacological suppression of PTEN that boosts neuronal intrinsic ability to grow enhances CST sprouting and regeneration after SCI. Transplantation of n...
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