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Funded Project Details - FY2021




Project Number:

I01RX002100-01A2
Title: Developing novel stem cell-based epigenetic approaches to treat hearing loss
Principal Investigator:

Zhengqing Hu

Location: Allen Park, MI
Congressional District Code: 13
Research Service: Rehabilitation R&D
Project Period: October 2018 - September 2022
FY 2021 Funding Amount: $279,375
Total Award Amount
(all years):
$1,100,000
Abstract: View full abstract and other project information on NIH RePORTER
Go To NIH RePORTER


Excerpt:

Project Summary Auditory hair cells are mechanotransduction receptors that convey sound signals to the brainstem via spiral ganglion neurons (SGNs). However, hair cells are vulnerable to a number of insults, including noise, blast, aging, and traumatic brain injury. Adult mammalian hair cell loss is usually irreversible, causing permanent hearing loss and other inner ear disorders. Currently, there are no biological approaches to replenish human hair cells. The long-term goal of this project is...



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