Office of Research & Development |
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Project Number: | I21RX002395-01A1 |
Title: | Neurobiological and Psychological Benefits of Exercise in Fibromyalgia and PTSD |
Principal Investigator: | Erica Scioli-Salter |
Location: | Boston, MA |
Congressional District Code: | 7 |
Research Service: | Rehabilitation R&D |
Project Period: | January 2018 - August 2022 |
FY 2021 Funding Amount: | $0 |
Total Award Amount (all years): |
$243,550 |
Abstract: |
View full abstract and other project information on NIH RePORTER Go To NIH RePORTER Excerpt: This study will compare the effects of a 12-week progressive exercise training program on 1) Fibromyalgia (FM) pain and PTSD symptoms, 2) pain threshold and tolerance, and 3) relevant biomarkers and neuromodulators including: a) anti-stress, anti-nociceptive, immune modulating factors such as neuropeptide Y (NPY) and GABAergic neuroactive steroids such as allopregnanolone and pregnanolone (together termed ALLO) b) factors that upregulate the expression of NPY and the GABAergic neuroactive steroi... |