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Funded Project Details - FY2021

Project Number:

Title: Neurobiological and Psychological Benefits of Exercise in Fibromyalgia and PTSD
Principal Investigator:

Erica Scioli-Salter

Location: Boston, MA
Congressional District Code: 7
Research Service: Rehabilitation R&D
Project Period: January 2018 - August 2022
FY 2021 Funding Amount: $0
Total Award Amount
(all years):
Abstract: View full abstract and other project information on NIH RePORTER


This study will compare the effects of a 12-week progressive exercise training program on 1) Fibromyalgia (FM) pain and PTSD symptoms, 2) pain threshold and tolerance, and 3) relevant biomarkers and neuromodulators including: a) anti-stress, anti-nociceptive, immune modulating factors such as neuropeptide Y (NPY) and GABAergic neuroactive steroids such as allopregnanolone and pregnanolone (together termed ALLO) b) factors that upregulate the expression of NPY and the GABAergic neuroactive steroi...

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