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Funded Project Details - FY2021

Project Number:

Title: Mechanisms of Adaptive and Maladaptive Responses of Renal Epithelium to Injury
Principal Investigator:

Raymond Harris

Location: Nashville, TN
Congressional District Code: 5
Research Service: Biomedical Laboratory R&D
Project Period: April 2018 - March 2022
FY 2021 Funding Amount: $156,800
Total Award Amount
(all years):
Abstract: View full abstract and other project information on NIH RePORTER


Abstract There is renewed awareness of the importance of the renal epithelium generally, and the proximal tubule specifically, as both a target and a mediator in chronic kidney diseases (CKD). Numerous studies have highlighted the importance of tubulointerstitial injury as an ultimate driver of progression of kidney disease. There is also increasing evidence that effective recovery of epithelial integrity following acute kidney injury (AKI) is vital to prevent development of CKD (1). Furthermor...

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