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Funded Project Details - FY2021




Project Number:

I01BX003919-01A1
Title: The role of Nampt in age-associated persistent lung fibrosis
Principal Investigator:

Louise Hecker

Location: Decatur, GA
Congressional District Code: 3
Research Service: Biomedical Laboratory R&D
Project Period: October 2017 - September 2022
FY 2021 Funding Amount: $248,800
Total Award Amount
(all years):
$1,188,030
Abstract: View full abstract and other project information on NIH RePORTER
Go To NIH RePORTER


Excerpt:

The pathophysiology of Idiopathic pulmonary fibrosis (IPF), a rapidly progressive and deadly fibrotic lung disease remains poorly understood. Aging is a well-recognized risk factor for IPF, and IPF disproportionately affects the aging veteran population. Given this shift in demographic, it is critical to understand the contribution of aging to the cellular/molecular mechanism(s) leading to the pathogenesis of age-related diseases, such as IPF. In resolving fibrosis, lung myofibroblasts (the key...



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