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Funded Project Details - FY2021




Project Number:

I01BX003859-01A1
Title: Mitochondrial metabolic modulation to minimize ischemic damage in donor heart
Principal Investigator:

Mohammed Quader

Location: Richmond, VA
Congressional District Code: 3
Research Service: Biomedical Laboratory R&D
Project Period: April 2018 - March 2022
FY 2021 Funding Amount: $156,800
Total Award Amount
(all years):
$699,276
Abstract: View full abstract and other project information on NIH RePORTER
Go To NIH RePORTER


Excerpt:

Patients with end stage heart failure (HF) require mechanical circulatory support, and if eligible, heart transplantation (HT) to save their life. Up to 20% of patients die while listed for heart transplantation. The supply of donor hearts has reached a plateau since the only current source of donor hearts consists of patients with irreversible severe brain damage (donation after brain death, DBD). Thus, there is an urgent need to expand the heart donor pool. A potential source of such donor hea...



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