Funded Project Details - FY2021
|Title:|| Autocrine/Paracrine Regulation of Intrahepatic Bile Duct Growth|
Gianfranco D. Alpini
|Congressional District Code:
||Biomedical Laboratory R&D
|| April 2018 -
|FY 2021 Funding Amount:
|Total Award Amount
View full abstract and other project information on NIH RePORTER
Go To NIH RePORTER
Nonalcoholic fatty liver disease (NAFLD) is an alarming public health concern and now considered the most common liver disease in the Western world. Patients with NAFLD may develop nonalcoholic steatohepatitis (NASH) of which many develop hepatic injury that may progress to cirrhosis. We have previously shown that in chronic cholestatic liver diseases, cholangiocytes, through the products of their cellular activation such as secretin (SCT), are the key link between bile duct injury and the subep...
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