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Funded Project Details - FY2021

Project Number:

Title: Regulation of Calcium Homeostasis in the Pancreatic Beta Cell
Principal Investigator:

Carmella Evans-Molina

Location: Indianapolis, IN
Congressional District Code: 7
Research Service: Biomedical Laboratory R&D
Project Period: October 2017 - September 2021
FY 2021 Funding Amount: $165,000
Total Award Amount
(all years):
Abstract: View full abstract and other project information on NIH RePORTER


The combined syndromes of type 1 (T1D) and type 2 (T2D) diabetes mellitus affect nearly one in four Veterans and over 422 million individuals worldwide. Inadequate insulin secretion from the pancreatic β cell plays a primary role in the pathogenesis of both major forms of diabetes. However, the mechanisms responsible for β cell failure in this disease remain poorly understood. The long-term goal of our research program is to delineate the role of altered β cell Ca2+ homeostasis in diabetes patho...

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