Talk to the Veterans Crisis Line now
U.S. flag
An official website of the United States government
ORD only    All VA Research websites

Office of Research & Development

print icon sign up for VA Research updates

Funded Project Details - FY2021

Project Number:

Title: The Role of Interleukin-17 Cytokines in GWVI Patients with IBS
Principal Investigator:

Joseph M Reynolds

Location: Hines, IL
Congressional District Code: 10
Research Service: Biomedical Laboratory R&D
Project Period: April 2018 - March 2021
FY 2021 Funding Amount: $0
Total Award Amount
(all years):
Abstract: View full abstract and other project information on NIH RePORTER


Gulf War Veterans' Illnesses (GWVI), a term encompassing an array of chronic and unexplained disease symptoms, is characterized by higher rates of gastrointestinal disorders in Veterans that served in the Gulf War compared to their non-deployed counterparts. Our previous work and work by others have identified a protective role for IL-17 and IL-17C in the intestinal epithelium with likely roles in protecting the barrier and halting the development of irritable bowel syndrome (IBS). The loss of I...

Questions about the R&D website? Email the Web Team.

Any health information on this website is strictly for informational purposes and is not intended as medical advice. It should not be used to diagnose or treat any condition.