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Funded Project Details - FY2021

Project Number:

Title: Neuroinflammatory and Epigenetic Mechanisms of Blood-Brain Barrier Compromise in Suicide
Principal Investigator:

Fatemeh G Haghighi

Location: Bronx, NY
Congressional District Code: 13
Research Service: Biomedical Laboratory R&D
Project Period: January 2018 - September 2022
FY 2021 Funding Amount: $191,800
Total Award Amount
(all years):
Abstract: View full abstract and other project information on NIH RePORTER


We propose a set of studies focused on the association of suicide with neuroinflammation and compromise of the blood-brain barrier, with the goal of identifying a pattern of quantifiable abnormalities that could serve as a biomarker for imminent suicidal risk in our Veterans. Autopsy studies are uniquely suited to do this, because they capture the state of the brain at the time of the suicidal act. Findings from our laboratories and others indicate that susceptibility to suicide includes inflam...

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