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Funded Project Details - FY2021




Project Number:

IK2RX002342-01A2
Title: The Effect of Estrogen Deficiencies on Vision Loss in Glaucoma
Principal Investigator:

Andrew J Feola

Location: Decatur, GA
Congressional District Code: 4
Research Service: Rehabilitation R&D
Project Period: April 2018 - March 2023
FY 2021 Funding Amount: $188,973
Total Award Amount
(all years):
$927,344
Abstract: View full abstract and other project information on NIH RePORTER
Go To NIH RePORTER


Excerpt:

Glaucoma is the largest cause of irreversible blindness in the world and is characterized by the loss of retinal ganglion cells (RGCs), which transmit visual information from the eye to the brain. While the exact cause of glaucoma is unknown, recent evidence has shown that early menopause in women is linked with developing glaucoma. Further, mutations in estrogen receptors and polymorphisms in the estrogen metabolic pathway are linked with glaucoma in both genders. However, since the number of w...



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