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Funded Project Details - FY2021




Project Number:

IK2RX002628-01A1
Title: Mimicking the Architecture and Modulus of Native Brain Tissue onto Neural Implants to Improve Biocompatibility
Principal Investigator:

Evon S. Ereifej

Location: Ann Arbor, MI
Congressional District Code: 11
Research Service: Rehabilitation R&D
Project Period: March 2018 - February 2022
FY 2021 Funding Amount: $184,174
Total Award Amount
(all years):
$730,898
Abstract: View full abstract and other project information on NIH RePORTER
Go To NIH RePORTER


Excerpt:

Electrical signals recorded from neurons by intracortical electrodes have been used by human patients to communicate with computers and to control robotic limbs. The signal quality and longevity of recordable signals are inconsistent. There is increasing evidence indicating that the neuro-inflammatory response may be a primary hurdle to consistently obtaining high quality recordings. Within the brain, cells are living in the elastic extracellular matrix (ECM) meshwork with 3D and high aspect rat...



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