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Funded Project Details - FY2021




Project Number:

I01CX001686-01A1
Title: Circulating Biomarkers for the Detection of Human Liver Diseases
Principal Investigator:

Courtney W. Houchen

Location: Oklahoma City, OK
Congressional District Code: 5
Research Service: Clinical Science R&D
Project Period: October 2018 - September 2022
FY 2021 Funding Amount: $165,000
Total Award Amount
(all years):
$695,000
Abstract: View full abstract and other project information on NIH RePORTER
Go To NIH RePORTER


Excerpt:

Hepatocellular Carcinoma (HCC) is the third most common cause of cancer-related deaths worldwide. The risk of liver fibrosis and HCC increases significantly in hepatitis C virus (HCV) carriers with obesity and diabetes, which is a rising trend in the USA. Thus, HCC represents a wide-ranging public health issue. Our recent studies have revealed a positive correlation between overexpression of doublecortin-like kinase (DCLK1) and cancers of the liver, colon, intestine and pancreas. Recently, we ha...



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