Value-Based Decision-Making Following Medial Temporal Lobe Lesions
Congressional District Code:
Clinical Science R&D
January 2019 -
FY 2021 Funding Amount:
Total Award Amount (all years):
View full abstract and other project information on NIH RePORTER Go To NIH RePORTER Excerpt:
Making optimal decisions depends on appreciation of the value of choices. An important source of information about the value of choices is prior experience: Positive experiences are more likely than negative ones to be selected again. Such value-based learning has long been considered the domain of trial-and-error incremental learning mediated by a cortico-striatal system. Recent evidence, however, suggests that in some conditions the medial temporal lobe (MTL), which mediates episodic memory, m...