Funded Project Details - FY2021
|Title:|| Barrier Dysfunction in Severe Surgical Diseases|
Douglas J. Turner
|Congressional District Code:
||Biomedical Laboratory R&D
|| October 2018 -
|FY 2021 Funding Amount:
|Total Award Amount
View full abstract and other project information on NIH RePORTER
Go To NIH RePORTER
Background/Rationale: Intestinal epithelial barrier integrity is critical for most gastrointestinal (GI) functions including digestion of food, as well as absorption and secretion of nutrients. The gastrointestinal mucosal layer is very vulnerable to injury resulting in loss of barrier integrity, and this occurs very commonly in critically ill Veteran patients in response to surgical stress. Preventing it would likely have a major impact on outcomes and costs for all critically ill Veteran popul...
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