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Project Number: | I01BX000113-08 |
| Title: | Barrier Dysfunction in Severe Surgical Diseases |
| Principal Investigator: | Douglas J. Turner |
| Location: | Baltimore, MD |
| Congressional District Code: | 7 |
| Research Service: | Biomedical Laboratory R&D |
| Project Period: | October 2018 - September 2022 |
| FY 2021 Funding Amount: | $156,800 |
| Total Award Amount (all years): |
$701,800 |
| Abstract: |
View full abstract and other project information on NIH RePORTER Go To NIH RePORTER Excerpt: Background/Rationale: Intestinal epithelial barrier integrity is critical for most gastrointestinal (GI) functions including digestion of food, as well as absorption and secretion of nutrients. The gastrointestinal mucosal layer is very vulnerable to injury resulting in loss of barrier integrity, and this occurs very commonly in critically ill Veteran patients in response to surgical stress. Preventing it would likely have a major impact on outcomes and costs for all critically ill Veteran popul... |