Rates and determinants of decreased bone health among HIV-infected patients
Congressional District Code:
Clinical Science R&D
October 2018 -
FY 2021 Funding Amount:
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View full abstract and other project information on NIH RePORTER Go To NIH RePORTER Excerpt:
HIV and HCV infections are associated with an increased risk of osteoporotic fractures (OF). HIV/HCV co- infected subjects have a 3-fold increased fracture incidence compared to uninfected individuals, and 50% greater risk than HIV mono-infected. Despite being associated with this much higher fracture risk, HIV/HCV co- infection is not associated with lower bone mineral density (BMD) than HIV alone. The increased OF risk associated with HCV is likely mediated by micro-architectural changes that...