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Project Number: | I01CX001566-01A1 |
| Title: | The role of functional iron deficiency in systemic complications of CKD |
| Principal Investigator: | Monique E Cho |
| Location: | Salt Lake City, UT |
| Congressional District Code: | 2 |
| Research Service: | Clinical Science R&D |
| Project Period: | July 2018 - June 2022 |
| FY 2021 Funding Amount: | $165,000 |
| Total Award Amount (all years): |
$681,619 |
| Abstract: |
View full abstract and other project information on NIH RePORTER Go To NIH RePORTER Excerpt: Veterans have disproportionately increased risks for cardiovascular (CV), diabetic, and chronic kidney diseases (CKD) compared to the general population. Abnormal iron homeostasis has recently been suggested to play a critical role in the pathogenesis of various metabolic and CV disorders. Iron metabolism disorder is highly prevalent in CKD, but its systemic extra-hematopoietic consequences, including diabetic, renal, and CV risks, have not been investigated. In CKD, induction of inflammatory si... |