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Funded Project Details - FY2021




Project Number:

I01CX001566-01A1
Title: The role of functional iron deficiency in systemic complications of CKD
Principal Investigator:

Monique E Cho

Location: Salt Lake City, UT
Congressional District Code: 2
Research Service: Clinical Science R&D
Project Period: July 2018 - June 2022
FY 2021 Funding Amount: $165,000
Total Award Amount
(all years):
$681,619
Abstract: View full abstract and other project information on NIH RePORTER
Go To NIH RePORTER


Excerpt:

Veterans have disproportionately increased risks for cardiovascular (CV), diabetic, and chronic kidney diseases (CKD) compared to the general population. Abnormal iron homeostasis has recently been suggested to play a critical role in the pathogenesis of various metabolic and CV disorders. Iron metabolism disorder is highly prevalent in CKD, but its systemic extra-hematopoietic consequences, including diabetic, renal, and CV risks, have not been investigated. In CKD, induction of inflammatory si...



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