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Funded Project Details - FY2021




Project Number:

I01CX001814-01
Title: Suvorexant: A Dual Orexin Receptor Antagonist for Treating Sleep Disturbance inPosttraumatic Stress
Principal Investigator:

Sabra S Inslicht

Location: San Francisco, CA
Congressional District Code: 12
Research Service: Clinical Science R&D
Project Period: January 2019 - December 2024
FY 2021 Funding Amount: $296,875
Total Award Amount
(all years):
$4,186,725
Abstract: View full abstract and other project information on NIH RePORTER
Go To NIH RePORTER


Excerpt:

Posttraumatic stress disorder (PTSD) is a common consequence of combat that is manifested in part by trauma-related hyperarousal and reactivity, seen in increased startle responses and impaired sleep that result from central and autonomic nervous system alterations. In fact, disturbed sleep is the most prevalent symptom endorsed by PTSD patients and is potentially debilitating in many domains of functioning (1, 2). As a relatively non-stigmatizing symptom, it is no surprise that disturbed sleep...



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