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Funded Project Details - FY2021

Project Number:

Title: Noradrenergic biomarkers in PTSD: precision medicine & mechanisms
Principal Investigator:

Rebecca Hendrickson

Location: Seattle, WA
Congressional District Code: 9
Research Service: Clinical Science R&D
Project Period: June 2018 - May 2023
FY 2021 Funding Amount: $399,589
Total Award Amount
(all years):
Abstract: View full abstract and other project information on NIH RePORTER


Background and Study Objective: Posttraumatic stress disorder (PTSD) affects as many as 15% of service members and Veterans following deployment. Current treatments are insufficient: most medications for PTSD decrease symptom intensity only moderately, and often appear to be less effective in Veterans than civilians. Prazosin, an antagonist of one of the major receptors for noradrenaline, has demonstrated significant efficacy for particularly hyperarousal symptoms and trauma nightmares in Vetera...

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