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Funded Project Details - FY2021




Project Number:

I01BX004037-01A1
Title: Interaction of GCSF with the Endocannabinoid System in Promoting Brain Repair
Principal Investigator:

Shijie Song

Location: Tampa, FL
Congressional District Code: 14
Research Service: Biomedical Laboratory R&D
Project Period: October 2018 - September 2022
FY 2021 Funding Amount: $289,650
Total Award Amount
(all years):
$1,424,784
Abstract: View full abstract and other project information on NIH RePORTER
Go To NIH RePORTER


Excerpt:

Background: G-CSF has been identified as a potential therapeutic agent for TBI. Administration of G- CSF soon after injury results in proliferation and release into the circulation of bone marrow-derived cells (BMDC). Monocytes from blood are recruited into the brain to the site of the lesion where they differentiate into microglia. These, in turn generate a number of neurotrophic factors and cytokines involved in repair and regenerative processes. Numerous studies indicate that TBI impacts the...



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