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Project Number: | IK2BX004338-01 |
| Title: | The role of mitochondrial dysfunction in ARDS after AKI |
| Principal Investigator: | Mark Hepokoski |
| Location: | San Diego, CA |
| Congressional District Code: | 52 |
| Research Service: | Biomedical Laboratory R&D |
| Project Period: | October 2018 - September 2023 |
| FY 2021 Funding Amount: | $317,030 |
| Total Award Amount (all years): |
$1,596,238 |
| Abstract: |
View full abstract and other project information on NIH RePORTER Go To NIH RePORTER Excerpt: Acute kidney injury (AKI) occurs in 30% of critically ill veterans, and the 6-year mortality rate is greater than 50%1,22. Interestingly, the leading causes of death in AKI are non-renal complications, and respiratory failure is the most serious non-renal complication of AKI with a worse prognosis than all other remote organ failures4. It is now recognized that there are mechanisms of respiratory failure in AKI beyond volume overload, such as the development of the acute respiratory distress syn... |