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Funded Project Details - FY2021




Project Number:

I01BX003821-01A1
Title: Immunogenetic control of autoimmune biliary disease
Principal Investigator:

William M Ridgway

Location: Martinez, CA
Congressional District Code: 1
Research Service: Biomedical Laboratory R&D
Project Period: April 2018 - September 2022
FY 2021 Funding Amount: $156,800
Total Award Amount
(all years):
$828,236
Abstract: View full abstract and other project information on NIH RePORTER
Go To NIH RePORTER


Excerpt:

Primary biliary cholangitis (PBC) is an incurable autoimmune biliary disease (“ABD”) in which the immune system destroys bile ducts by targeting cholangiocytes. Many immune based therapies have been applied to PBC, but none have been successful and the disease is currently incurable. Progress in finding new therapies for PBC has been blocked because the clinical symptoms of disease often arise many years after initiation of disease; thus data derived from human patients has not permitted fundame...



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