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Funded Project Details - FY2021




Project Number:

I01BX000508-09A1
Title: Guidance of pulmonary fibroblast migration during alveolar septal formation
Principal Investigator:

Stephen E. McGowan

Location: Iowa City, IA
Congressional District Code: 2
Research Service: Biomedical Laboratory R&D
Project Period: October 2018 - September 2022
FY 2021 Funding Amount: $156,800
Total Award Amount
(all years):
$701,800
Abstract: View full abstract and other project information on NIH RePORTER
Go To NIH RePORTER


Excerpt:

Destructive parenchymal lung diseases such as emphysema and pulmonary fibrosis are largely irreversible, and strategies for eliciting alveolar repair and regeneration are an important priority. This application addresses mechanisms which guide alveolar fibroblasts to optimal locations for generation of a coherent, mechanically integrated elastic and collagen fiber network. Learning how signaling platforms integrate and condition signals from the extracellular environment during alveolar developm...



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