Funded Project Details - FY2021
|Title:|| Guidance of pulmonary fibroblast migration during alveolar septal formation|
Stephen E. McGowan
||Iowa City, IA
|Congressional District Code:
||Biomedical Laboratory R&D
|| October 2018 -
|FY 2021 Funding Amount:
|Total Award Amount
View full abstract and other project information on NIH RePORTER
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Destructive parenchymal lung diseases such as emphysema and pulmonary fibrosis are largely irreversible, and strategies for eliciting alveolar repair and regeneration are an important priority. This application addresses mechanisms which guide alveolar fibroblasts to optimal locations for generation of a coherent, mechanically integrated elastic and collagen fiber network. Learning how signaling platforms integrate and condition signals from the extracellular environment during alveolar developm...
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