Talk to the Veterans Crisis Line now
U.S. flag
An official website of the United States government

Office of Research & Development

print icon sign up for VA Research updates

Funded Project Details - FY2023




Project Number:

I01BX004024-01A1
Title: Purinergic control of calcium flux in podocytes
Principal Investigator:

Alexander Staruschenko

Location: Milwaukee, WI
Congressional District Code: 4
Research Service: Biomedical Laboratory R&D
Project Period: October 2018 - September 2023
FY 2023 Funding Amount: $209,988
Total Award Amount
(all years):
$1,031,535
Abstract: View full abstract and other project information on NIH RePORTER
Go To NIH RePORTER


Excerpt:

The podocyte has become a crucial focus as a target for interventions in kidney disease due to its key role in regulating glomerular permeability and maintaining glomerular structure. Podocyte injury is believed to be pathogenetically and prognostically important in diabetic nephropathy (DN). One of the main factors determining pathological changes of glomerular morphology and permeability are linked to elevation of podocyte intracellular calcium ([Ca2+]i). Transient receptor potential canonical...



Questions about the R&D website? Email the Web Team

Any health information on this website is strictly for informational purposes and is not intended as medical advice. It should not be used to diagnose or treat any condition.