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Project Number: | I01BX002316-05A1 |
| Title: | Estrogen receptor and the cardiovascular system |
| Principal Investigator: | Ellis R. Levin |
| Location: | Long Beach, CA |
| Congressional District Code: | 47 |
| Research Service: | Biomedical Laboratory R&D |
| Project Period: | October 2018 - September 2022 |
| FY 2021 Funding Amount: | $156,767 |
| Total Award Amount (all years): |
$757,631 |
| Abstract: |
View full abstract and other project information on NIH RePORTER Go To NIH RePORTER Excerpt: Project Summary/Abstract Estrogen action has been shown in animal models and to an extent in humans to mitigate various forms of cardiovascular disease, including hypertension, atherosclerosis, and ischemia/reperfusion injury. Estrogen acts at its receptors, ERalpha and ERbeta. There is also strong data that estrogen prevents the development of cardiac hypertrophy, fibrosis, and progression to heart failure, particularly in human-relevant animal models when started early in the course of disease... |