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Funded Project Details - FY2021




Project Number:

I01BX003933-01A2
Title: Regulation of Renal Injury and Fibrosis by the Plasminogen Receptor, Plg-RKT
Principal Investigator:

Robert J. Parmer

Location: San Diego, CA
Congressional District Code: 52
Research Service: Biomedical Laboratory R&D
Project Period: April 2018 - March 2022
FY 2021 Funding Amount: $156,800
Total Award Amount
(all years):
$667,559
Abstract: View full abstract and other project information on NIH RePORTER
Go To NIH RePORTER


Excerpt:

Chronic kidney disease (CKD) has emerged as a silent killer that affects a large segment (15-20%) of the adult population, and is a major risk factor for end-stage renal disease (ESRD), as well as acute kidney injury, cardiovascular disease, and premature death. Progressive tubulointerstitial fibrosis is the final common pathway for all kidney diseases leading to CKD. However, the molecular mechanisms and regulatory steps that govern and modulate tubulointerstitial fibrogenesis are not fully und...



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