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Funded Project Details - FY2021

Project Number:

Title: The role of PI3K in pancreatic cancer genetics and progression
Principal Investigator:

Richard Z. Lin

Location: Northport, NY
Congressional District Code: 3
Research Service: Biomedical Laboratory R&D
Project Period: July 2018 - June 2022
FY 2021 Funding Amount: $156,800
Total Award Amount
(all years):
Abstract: View full abstract and other project information on NIH RePORTER


Pancreatic ductal adenocarcinoma (PDAC) is the third leading cause of cancer-related death in the U.S.A., with a five-year survival rate of 4%. It is also a major cause of mortality among the VA patient population. There is great urgency to identify new therapeutic strategies for PDAC because current treatments have little impact on patient survival. More than 90% of PDACs have oncogenic mutations in the Kras gene. The phosphoinositide 3-kinase p110α catalytic subunit (gene name Pik3ca) is a dow...

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