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Funded Project Details - FY2021

Project Number:

Title: Hydroxynorketamine for the Treatment of PTSD and Anhedonia
Principal Investigator:

Todd Gould

Location: Baltimore, MD
Congressional District Code: 7
Research Service: Biomedical Laboratory R&D
Project Period: October 2018 - September 2022
FY 2021 Funding Amount: $286,907
Total Award Amount
(all years):
Abstract: View full abstract and other project information on NIH RePORTER


Deleterious psychiatric outcomes following stress afflict many recently deployed combat Veterans. Recent evidence has shown that low doses of the anesthetic ketamine rapidly ameliorate depression, posttraumatic stress disorder (PTSD), anhedonia (a reduced capacity to experience pleasure), and suicidality within hours following a single administration. These effects extend to treatment-resistant populations, implicating ketamine as a novel and unique pharmacological option for treating psychiatri...

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