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Funded Project Details - FY2021




Project Number:

I01BX004356-01
Title: Exercise-Induced Shear Stress Modulates Metabolic Pathways for Vascular Repair and Protection
Principal Investigator:

Tzung K Hsiai

Location: West Los Angeles, CA
Congressional District Code: 33
Research Service: Biomedical Laboratory R&D
Project Period: January 2019 - December 2022
FY 2021 Funding Amount: $156,800
Total Award Amount
(all years):
$759,779
Abstract: View full abstract and other project information on NIH RePORTER
Go To NIH RePORTER


Excerpt:

Exercise-Induced Shear Stress Modulates Metabolic Pathways for Vascular Repair and Protection Cardiovascular and metabolic diseases are on the rise in our veterans returning from battlefields in Afghanistan and the Middle East, and exercise intervention remains an effective lifestyle modification. Hemodynamic stress forces modulate both metabolic and mechanical effects on vascular endothelial cells, mediating the focal and eccentric nature of atherosclerotic lesions. The advent in metabolomics a...



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