Talk to the Veterans Crisis Line now
U.S. flag
An official website of the United States government

Office of Research & Development

print icon sign up for VA Research updates

Funded Project Details - FY2021




Project Number:

I01BX004133-01A1
Title: Mechanisms of imbalanced inward and outward arteriovenous fistula remodeling
Principal Investigator:

Yan-Ting E Shiu

Location: Salt Lake City, UT
Congressional District Code: 2
Research Service: Biomedical Laboratory R&D
Project Period: October 2018 - September 2022
FY 2021 Funding Amount: $234,569
Total Award Amount
(all years):
$1,157,220
Abstract: View full abstract and other project information on NIH RePORTER
Go To NIH RePORTER


Excerpt:

The inability of arteriovenous fistulas (AVFs) to mature sufficiently for adequate dialysis is a major clinical problem confronting chronic hemodialysis. Up to 60% of newly created AVFs fail to mature, and currently there is no effective strategy to enhance AVF maturation. AVF maturation failure results from an imbalance between inward remodeling due to venous neointimal hyperplasia and outward remodeling due to sustained venous dilation. Although inward remodeling has been intensively studied,...



Questions about the R&D website? Email the Web Team.

Any health information on this website is strictly for informational purposes and is not intended as medical advice. It should not be used to diagnose or treat any condition.