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Funded Project Details - FY2021

Project Number:

Title: Oxygen, Pulmonary Innate Immunity and Alveolar Epithelial Cell GM-CSF
Principal Investigator:

Robert Paine

Location: Salt Lake City, UT
Congressional District Code: 2
Research Service: Biomedical Laboratory R&D
Project Period: July 2018 - June 2022
FY 2021 Funding Amount: $156,668
Total Award Amount
(all years):
Abstract: View full abstract and other project information on NIH RePORTER


Pulmonary innate immune responses depend upon a highly regulated multicellular network to defend an enormous surface area of interaction with the external world. Disruption of these responses renders the host susceptible to pneumonia and subsequent systemic spread of infection. This proposal is to investigate the impact of local variation in oxygenation within the lung on key aspects of this host defense network. Heterogeneous ventilation is a common feature of many pulmonary conditions, includi...

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