Funded Project Details - FY2021
|Title:|| Assessing the role of metabolism in monocyte to macrophage differentiation in pulmonary fibrosis|
G. R.Scott Budinger
|Congressional District Code:
||Clinical Science R&D
|| October 2018 -
|FY 2021 Funding Amount:
|Total Award Amount
View full abstract and other project information on NIH RePORTER
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Project Summary Idiopathic Pulmonary Fibrosis (IPF) has a prognosis worse than most cancers, with only 20-30 percent of patients surviving 5 years after diagnosis. The pathophysiology in IPF relates to dysregulated repair after injury to the alveolo-capillary though the mechanisms that link alveolar capillary membrane injury with fibroblast activation and disordered repair are incompletely understood. In a recent publication we provide clear genetic evidence that alveolar macrophages are key eff...
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