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Funded Project Details - FY2021




Project Number:

I01RX001222-05A2
Title: Muscle stem cell therapy for volumetric muscle loss
Principal Investigator:

Thomas A. Rando

Location: Palo Alto, CA
Congressional District Code: 18
Research Service: Rehabilitation R&D
Project Period: November 2018 - October 2022
FY 2021 Funding Amount: $275,000
Total Award Amount
(all years):
$1,100,000
Abstract: View full abstract and other project information on NIH RePORTER
Go To NIH RePORTER


Excerpt:

Major trauma can cause volumetric muscle loss (VML) resulting in life-long disability. Although skeletal muscle is capable of remarkable regenerative potential, when injury is massive and destroys the underlying architecture, regeneration is aborted and is characterized instead by scar tissue formation. The standard of care in such injuries is wound closure, leaving little hope for functional recovery. The promise of regenerative medicine is the full regeneration of damaged tissues, either by pr...



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