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Project Number: | I01RX002689-01A2 |
| Title: | Targeting Mast Cells in Post-Traumatic Joint Rehabilitation and Osteoarthritis |
| Principal Investigator: | William H. Robinson |
| Location: | Palo Alto, CA |
| Congressional District Code: | 18 |
| Research Service: | Rehabilitation R&D |
| Project Period: | November 2018 - October 2022 |
| FY 2021 Funding Amount: | $275,001 |
| Total Award Amount (all years): |
$1,100,001 |
| Abstract: |
View full abstract and other project information on NIH RePORTER Go To NIH RePORTER Excerpt: Many Veterans and civilians sustain traumatic joint injuries, which frequently lead to poor rehabilitation outcomes, joint dysfunction, and development of osteoarthritis (OA) in the injured joint. Existing treatments for joint injury and OA only alleviate symptoms, and are ineffective in promoting healing or preventing OA. Increasing evidence implicates “low-grade” inflammation following joint injury in poor rehabilitation outcomes, and in the eventual development of post-traumatic OA. A better... |