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Funded Project Details - FY2021




Project Number:

I01RX002689-01A2
Title: Targeting Mast Cells in Post-Traumatic Joint Rehabilitation and Osteoarthritis
Principal Investigator:

William H. Robinson

Location: Palo Alto, CA
Congressional District Code: 18
Research Service: Rehabilitation R&D
Project Period: November 2018 - October 2022
FY 2021 Funding Amount: $275,001
Total Award Amount
(all years):
$1,100,001
Abstract: View full abstract and other project information on NIH RePORTER
Go To NIH RePORTER


Excerpt:

Many Veterans and civilians sustain traumatic joint injuries, which frequently lead to poor rehabilitation outcomes, joint dysfunction, and development of osteoarthritis (OA) in the injured joint. Existing treatments for joint injury and OA only alleviate symptoms, and are ineffective in promoting healing or preventing OA. Increasing evidence implicates “low-grade” inflammation following joint injury in poor rehabilitation outcomes, and in the eventual development of post-traumatic OA. A better...



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