Funded Project Details - FY2021
|Title:|| Novel Regenerative Therapeutic in Chronic Complex TBI|
Christine E. Marx
|Congressional District Code:
|| July 2019 -
|FY 2021 Funding Amount:
|Total Award Amount
View full abstract and other project information on NIH RePORTER
Go To NIH RePORTER
Novel Regenerative Therapeutic in Chronic Complex TBI Allopregnanolone (ALLO) is a neurosteroid endogenously produced in brain that exhibits pleiotropic actions highly relevant to the neurobiology and treatment of chronic complex TBI. ALLO exhibits pronounced regenerative actions, in addition to marked neuroprotective, analgesic, and anti-inflammatory effects in rodent models. Furthermore, our recent human data suggest that ALLO is decreased in TBI, suggesting that ameliorating deficits of this...
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