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Funded Project Details - FY2021

Project Number:

Title: Heart Function Decline and Aging
Principal Investigator:

Wolfgang Dillmann

Location: San Diego, CA
Congressional District Code: 52
Research Service: Biomedical Laboratory R&D
Project Period: January 2019 - December 2022
FY 2021 Funding Amount: $156,800
Total Award Amount
(all years):
Abstract: View full abstract and other project information on NIH RePORTER


Heart failure (HF) is a significant health problem in the elderly population, including in Veterans. The basis for the diminished function of the old heart (OH, 19-22 month) and increased propensity to develop HF is only incompletely explored and poorly treated. Preliminary results show that in OH cardiac function is diminished, cardiac myocytes (CM) contract poorly, and decreased Mitochondrial (Mito) respiratory function occurs. Our preliminary results also show novel findings that in CM from O...

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